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Research Specialist, Genomics

Pennington Reserve at Upper Providence, Pennsylvania

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Responsibilities

Location Upper Providence, PennsylvaniaUS Job ID JR-032941

Key Responsibilities

Customer Support

  • Work with the Customer and PerkinElmer staff to ensure quality and compliance of work and activities carried out within the laboratory.
  • Develop target relevant cell-based assays; optimize, validate, and troubleshoot screening assay robustness, sensitivity, reproducibility; convert assays into HT screening format.
  • Maintain mammalian cell cultures, optimize and utilize gene editing technologies (CRISPR, RNAi) to develop in vitro functional models and perform high-throughput screens.
  • Ensure all tasks and responsibilities are performed according to industry-leading scientific and ethical standards and accurately documented in lab electronic notebook system
  • Analyze, synthesize, and communicate data to both technical and non-technical colleagues and collaborators
  • Generate and analyze data with the highest Data Integrity standards.
  • The leader will also interface with key customer contacts to ensure KPIs are being hit and customer satisfaction is at a high level.
  • Work in collaboration with Customer line safety reps to ensure a high level of safety is maintained in the lab. Continue technological improvements to increase productivity and cost-efficiency.
  • Data reporting, management, and interactions as appropriate with the teams.
  • Ensure compliance with all R&D data integrity practices, ethics codes, standards and training, and safety training and practice
  • Support customer desired growth by identifying activities in which we can provide additional services, working with all critical PerkinElmer and customer team members and following proper approval processes.

Basic Qualifications:

  • B.S. or M.S with 2 years of research experience or PhD in cell biology, biochemistry, pharmacology, or related field with with the ability to succeed in a collaborative, matrix environment.
  • Experience in RNAi/CRISPR gene editing using various methods such as electroporation, lipid transfection, lentivirus infections.
  • Experience with standard in vitro biochemical and cell-based assays (e.g. reporter gene, protein translocation, HTRF, ELISA etc.), including assay transfer, execution and troubleshooting.

Preferred Qualifications:

  • Experience in molecular biology techniques, including but not limit to qPCR and Western Blot.
  • Computational skills preferred for enabling automated data acquisition and analysis, and familiarity with related data analysis applications, example Spotfire and PRISM.
  • Experience within the pharmaceutical industry as highly preferred.
  • Experience in developing protocols and utilization of liquid handling platforms such as the Hamilton STAR and Labcyte Echo as well as plate readers like BMG Pherastar.
  • Experience using Microsoft 365, including Outlook, Teams, Word, Excel and others.
  • Strong communication skills both written and verbal.
  • Self-motivated and able to work under pressure to prioritize conflicting deadlines. 
  • Service orientated attitude combined with innovative thinking.
  • Knowledge of laboratory safety practices as defined by the Company and/or the customer’s site safety code.
  • Strong interpersonal skills; strong team player with customer satisfaction focus

Working Conditions

  • The primary working conditions associated with this position is dependent on the specific customer site and the types of services we support at the site.  Conditions can vary anywhere from office areas, lab spaces, to freight elevators etc.
  • Employee may be required to manage hazardous wastes in compliance with company procedures & State/Federal/Local hazardous waste regulations. Duties may include; Identifying, handling, generating, accumulating, storing, labeling.
  • Must be able to work in a laboratory, controlled environments requiring personal protective equipment.
  • Work with biohazards such as blood borne pathogens.
  • Ensure safety, security, and the environment in all aspects of the daily activities, and any potential safety hazards are addressed and corrected immediately.
  • Understand the ergonomic relationship between people, equipment, and the working environment.
  • Must be able to work in a laboratory, controlled environments requiring personal protective equipment.

Other Requirements:

  • Must be able to remain in a stationary position for more than 25% of the time.
  • The person in this position needs to regularly move inside and outside the lab
  • Frequently operate on instruments, objects, tools or controls, which will require regularly bending, squatting, stretching and reaching in order to complete tasks.
  • Regularly move or lift 25 pounds, up to 50 pounds, of laboratory equipment and machinery.
  • Constantly operates a computer and other office productivity machinery, such as a calculator, copy machine, and computer printer.
  • Specific vision abilities required by this position include without limitation, the ability to observe details at close range (within a few feet of the instrument), distance vision, color vision, peripheral vision, depth perception, and ability to adjust focus in order to perform the essential service functions of this position.
  • Use of personal protective equipment in laboratory.
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PerkinElmer is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability status, age, or veteran status or any other characteristics protected by applicable law. PerkinElmer is committed to a culturally diverse workforce.

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