Core Flow Support Specialist
South San Francisco, California
Responsibilities
Location South San Francisco, CaliforniaUS Job ID REQ-056772The Cytometric Profiling group within the Profiling & Expression department is seeking a motivated, creative scientist to advance preclinical immunology and oncology drug development in a highly collaborative environment.
The qualified candidate will generate and analyze high-quality data to support immune profiling, biomarker discovery, and platform development, while contributing to the day-to-day operations of the Flow Cytometry Core Lab.
Key Responsibilities
- Perform immunophenotyping of human and non-human primate blood and tissue using high-dimensional flow cytometry
- Identify and validate target engagement and pharmacodynamic biomarkers for preclinical drug development
- Apply single-cell technologies to enable target identification and biomarker discovery
- Develop and execute functional assays using therapeutic antibodies
- Evaluate novel technologies and contribute to platform development
- Support daily operations within the Flow Cytometry Core Lab (instrument startup, shutdown, and daily QC)
- Present data clearly in team meetings and actively participate in scientific discussions
Educational Requirements
BS/MS in Immunology, Biology, or related field with 5–8 years of relevant industry experience; or PhD in Immunology with 1–3 years of relevant industry experience
Required Experience and Skills
- Strong foundation in immunology
- Expertise in aseptic cell culture and primary cell isolation from human blood and tissues
- Specialization in multi-color flow cytometry (preferably with BD Biosciences or Beckman Coulter instruments) and data analysis using FlowJo
- Experience with high-dimensional spectral flow cytometry (preferably with Cytek Aurora) and data analysis (SpectroFlo)
- Experience developing functional assays and measuring secreted cytokines (ELISA, MSD, Luminex)
- Excellent communication and interpersonal skills
- Meticulous attention to detail with strong record-keeping practices
- Lab-based role - onsite presence is required on all working days
Preferred Skills
- Experience with fluorescence-activated cell sorting
- Experience with single-cell genomics (10x Genomics, BD Rhapsody, HIVE-seq) and/or single-cell proteomics (IsoPlexis)
- Proficiency with data analysis/visualization tools (TIBCO Spotfire, GraphPad Prism, IsoSpeak) and familiarity with high-dimensional data analysis methods (UMAP/t-SNE, clustering)
The annual compensation range for this full-time position is $160,000.00 to $170,000.00. The final base pay offered to the successful candidate will be determined by factors including internal equity, work location, as well as individual qualifications, such as job-related skills, experience, and relevant education or training.
PerkinElmer is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability status, age, or veteran status or any other characteristics protected by applicable law. PerkinElmer is committed to a culturally diverse workforce.
