Research Associate - Antibody Development
San Diego, California
Responsibilities
Location San Diego, CaliforniaUS Job ID JR-035171BioLegend, Inc. (a PerkinElmer Company) develops world-class, cutting-edge antibodies and reagents for biomedical research, manufactured in our state-of-the-art facility in San Diego, CA. Our mission is to accelerate research and discovery by providing the highest quality products at an outstanding value, along with superior customer service and technical support. Our product expertise covers a diverse set of research areas including Immunology, Neuroscience, Cancer, Stem cells, and Cell Biology.
In 2021, PerkinElmer, Inc. (NYSE: PKI) a global leader committed to innovating for a healthier world, acquired BioLegend. The acquisition, the largest in PerkinElmer’s history, further expands the Company’s life science franchise into high-growth areas such as cytometry, proteogenomics, multiplex assays, recombinant proteins, magnetic cell separation and bioprocessing.
Job Summary
This position is responsible for producing monoclonal antibodies derived from various materials such as hybridoma cultures. Basic tissue culture and/or purification responsibilities include performing cell culture work, antibody purification and associated quality control steps including purity analysis, isotype testing, mycoplasma detection, Ig quantitation, and specificity measurement by assigned methods. Detailed performance documentation, database entry and report preparation are also required. In addition, efforts for technical troubleshooting, inventory and laboratory maintenance will be expected to support team.
Essential Functions
Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Tissue Culture Function
- Perform cell culture activities including thawing, maintenance, freezing with sterile technique
- Perform various analytical measurements to determine cell culture conditions
Purification Function
- Conduct antibody purification steps to meet required specifications
- Biochemical characterization of the purified antibodies by assigned techniques such as gel electrophoresis, analytical chromatography and other methods
General Function
- Enforce lab safety and ISO13485/ cGMP quality regulations
- Keep good work records following good document practices
- Work data entry into databases
- Preparation reports as requested
- Perform basic laboratory equipment maintenance
- Maintain material, product and laboratory supply inventories
- Other duties as assigned to support the team priorities and goals
- Other projects or responsibilities as may be required.
iACT Competencies
- innovate – Be better, keep improving, be more efficient, creative, and be in the forefront of development
- Aspire – Have desire, purpose, and ambition challenging ourselves to push the limits and reach new heights
- Collaborate – Foster teamwork, common goals, selflessness, communication and mutual support
- Transform – Adapt, learn, re-invent and change for future development and growth
Minimum Qualifications – Education and Experience
- Bachelor of Science or equivalent degree with a course works in cell biology, immunology, and biochemistry
Preferred Qualifications – Education and Experience
- Basic knowledge of immunological assays and protein purification is preferred
- Knowledge of mammalian cell culture/ cell line maintenance; antibody purification and application is also preferred
- Previous experience of antibody development is a strong plus
- Prior working experiences in an ISO 13485 or cGXP environment is a plus
*Please note that this position is scheduled to start mid March - early April.
The anticipated salary range for candidates who will work at BioLegend in San Diego, California is$26.44 to $30.41(hourly).The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to: the type and length of experience within the job, type and length of experience within the industry, education, etc. BioLegend is a multi-state employer and this salary range may not reflect positions that work in other states.
Work Environment & Physical Demands
Lab
While performing the duties of this job, the employee regularly works in a laboratory environment with occasional data entry on a computer. Occasional exposure to a warehouse environment.
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
While performing the duties of this job, the employee is regularly required to use hands and fingers to handle, feel, or operate objects, tools or controls, and reach with hands and arms. The employee is frequently required to stand, talk and hear.
Condition of Employment
Concerns regarding COVID-19 continue as positive cases are experienced in the communities in which we operate. Please be aware that, as a condition of employment, BioLegend requires proof of COVID vaccination for all U.S.-based employees (subject to limited exceptions) beginning January 18, 2022.
PerkinElmer is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability status, age, or veteran status or any other characteristics protected by applicable law. PerkinElmer is committed to a culturally diverse workforce.